Laboratory of Macromolecular Crystallography

Tatiana P. Skovoroda

Date and place of birth: 6 September 1953, Kirov

Position: research fellow, LMC, IMPB RAS.


1970-1975 - graduate student of the Novosibirsk State University;

1978-1981 - postgraduate student of the Moscow State Educational Institute (Mathematical Department).

Previous positions:

  • from 1997 - research fellow of LMC;
  • 1985 - 1997 - junior research fellow of LMC;
  • 1982 - 1985 - junior research fellow of LMM and Computers Department.

Research interests:

  • the spatial structure of biological macromolecules;
  • development of software for molecular biology studies.

Grants (participant):

  • 1992-1994 grant of the Scientific Council "Cell-free protein synthesis";
  • 1993-1994 grant of ACA/USNCCr Fund;
  • 1994 grant RMZ000 of International Science Foundation
  • 1995 grant RMZ300 of International Science Foundation;
  • 1994-1996 grant 94-04-12844 of Russian Foundation for Basic Researches;
  • 1997-1999 grant 97-04-48319 of Russian Foundation for Basic Researches;
  • 2000-2002 grant 00-04-48175 of Russian Foundation for Basic Researches;
  • 2003-2005 grant 03-04-48155 of Russian Foundation for Basic Researches;

Projects participation:

Projects details

  • The development of an ab-initio procedure for solution of the crystallographic phase problem starting from the low resolution.
  • The use of the maximal likelihood principle in protein crystallography.
  • The development of crystallographic software.
  • The use of Fourier syntheses histograms for solution of the phase problem in protein crystallography.
  • Ab-initio low-resolution phasing in crystallography of macromolecules by maximisation of the likelihood.
  • A statistical approach to the estimates of errors in the phases calculated from a preliminary atomic models.


15 publications including then 8 full articles.

The list of publications.

The full texts of papers.


Postal address:

Skovoroda T.P.
Institute of Mathematical Problems of Biology RAS,
Pushchino, Moscow Region,
142290, Russia