Structure

Laboratory of Macromolecular Crystallography


Tatiana E. Petrova


Date and place of birth: 21 May 1964, Kursk

Degree: Ph.D. in physics and mathematics (with specialization in biophysics)

Position: senior research fellow of Laboratory of Macromolecular Crystallography, Institute of Mathematical Problems of Biology RAS.

Education

1981-1987 - graduate student of the Moscow State University (Physics department); the master degree thesis: "Membrane control with pressure".

Degree

2000 - PhD degree awarded by the Institute of Theoretical and Experimental Biophysics RAS (Pushchino) for the thesis " Ab-initio low-resolution phasing in crystallography of macromolecules by maximization of the likelihood ".

Previous positions:

  • from 2002 - senior research fellow of LMC;
  • 2000 - 2002 - research fellow of LMC;
  • 1996 - 2000 - jounior research fellow of LMC;
  • 1992 - 1996 - engineer-mathematition of LMC;
  • 1991 - 1992 - engineer-programmer of LMC;
  • 1988 - 1989 - engineer-programmer;
  • 1987 -1988 - engineer in Biological Experiments Automation Laboratory.

Research interests:

  • mathematical and computer problems of X-ray structure analysis.

Grants (participant):

  • 1994 grant RMZ000 of International Science Foundation
  • 1995 grant RMZ300 of International Science Foundation;
  • 1994-1996 grant 94-04-12844 of Russian Foundation for Basic Researches;
  • 1997-1999 grant 97-04-48319 of Russian Foundation for Basic Researches;
  • 2000-2002 grant 00-04-48175 of Russian Foundation for Basic Researches;

Projects participation:

Projects details

  • The development of an ab-initio procedure for solution of the crystallographic phase problem starting from the low resolution.
  • The use of the maximal likelihood principle in protein crystallography.
  • The development of Few Atoms Model method for solution of the phase problem in protein crystallography.
  • Ab-initio low-resolution phasing in crystallography of macromolecules by maximization of the likelihood.
  • The studies performed in 2001-2002 in CNRS-GIF, LGV (Gif-sur-Yvette, France), P.I. J.Navaza:
    • A new protocol for AmoRe program complex.

Publications:

More then 20 publications including more then 10 full articles.

The list of publications.

The full texts of papers.

E-mail:

petrova@impb.psn.ru

Postal address:

Petrova T.E.
Institute of Mathematical Problems of Biology RAS,
Pushchino, Moscow Region,
142290, Russia