Structure

Laboratory of Macromolecular Crystallography


Natalia L. Lunina


Date and place of birth: 12 August 1951, Makeevka, Ukraine

Degree:Ph.D. in physics and mathematics (with specialization in biophysics)

Current position: Senior research fellow in Laboratory of Macromolecular Crystallography, Institute of Mathematical Problems of Biology RAS.

Education

1967-1968 - Specialized physics and mathematics boarding school under Kiev State University;

1968-1973 - graduate student of the Moscow State University (department of Mathematics and Mechanics); the master degree thesis: "Some mathematical models in radiobiology".

Degree

1999 - PhD degree awarded by the Institute of Theoretical and Experimental Biophysics RAS (Pushchino) for the thesis "Computer approaches to solution of the phase problem of macromolecular crystallography at low resolution".


Previous positions:

  • from 2000 - senior research fellow; IMPB RAS, Pushchino;
  • 1989-2000 - engineer-programmer, further leader engineer-programmer of Laboratory of Computational Mathematics of Research Computer Centre (from 1992 - IMPB RAN);
  • 1978-1989 - senior engineer-mathematician, further senior engineer-programmer of Computers Department of Research Computer Centre;
  • 1977-1978 - senior engineer in Soil Processes Modeling Laboratory of the Institute of Agrochemistry and Soil Science of the USSR Acad.Sci., Pushchino; engineer-programmer of Computers Department of Research Computer Centre, Pushchino;
  • 1973-1977 engineer of software of Information Computer Centre, Electrostal, Moscow region.

Research interests:

  • the spatial structure of biological macromolecules;
  • development of software for molecular biology studies;
  • teaching of secondary school students for the computer science;
  • development of teaching software for the secondary school.

Awards:

  • 1988 - the 1st degree diploma in the contest in development of teaching software (Leningrad, 1988)

Grants (participant):

  • 1992-1994 grant of the Scientific Council "Cell-free protein synthesis";
  • 1993-1994 grant of ACA/USNCCr Fund;
  • 1994 grant RMZ000 of International Science Foundation
  • 1995 grant RMZ300 of International Science Foundation;
  • 1994-1996 grant 94-04-12844 of Russian Foundation for Basic Researches;
  • 1997-1999 grant 97-04-48319 of Russian Foundation for Basic Researches;
  • 2000-2002 grant 00-04-48175 of Russian Foundation for Basic Researches;
  • 1993-2002 support by the collaborative program of Russian Academy of Sciences and National Centre for Scientific Researches (CNRS, France);
  • 2002-2003 grant 02-02 of French-Russian Institute A.M.Liapunov of Informatics and Applied Mathematics
  • 2000-2002 grant 03-04-48155 of Russian Foundation for Basic Researches;

Projects participation:

Projects details

  • The development of an ab-initio procedure for solution of the crystallographic phase problem starting from the low resolution.
  • The use of the maximal likelihood principle in protein crystallography.
  • The determination of structures of biological macromolecules.
  • The development of crystallographic software.
  • The use of the connectivity properties of high-density regions for solution of the phase problem in macromolecular crystallography
  • The development of Few Atoms Model method for solution of the phase problem in protein crystallography.
  • The teaching of secondary school students for the computer science. (1981-1990).
  • The development of teaching software for the secondary school. (1986-1993).
  • The treatment of nucleotide sequences. The first steps (HEID-package). (1984).

Publications:

More then 60 publications including more then 30 full articles.

The list of publications.

The full texts of papers.

E-mail:

lunina@impb.psn.ru

Postal address:

Lunina N.L.
Institute of Mathematical Problems of Biology RAS,
Pushchino, Moscow Region,
142290, Russia